Lives listing by nationality: English
- Saint Amand, James (born 1687–died 1754), English scholar, classicist, bibliophile, collector
- The Saint James’s Chronicle (founded 1761), English newspaper
- Saint Paul, Horace (born 1729–died 1812), English soldier of fortune, army officer, diplomat
- Saint Quintin, Sir William, 3rd baronet (born 1662–died 1723), English politician, member of Parliament, civil servant
- Salisbury, William (died 1823/1829), English nurseryman, botanist, horticulturist
- Salmon, Thomas (born 1679–died 1767), English author, historian, travel-writer
- Salusbury, Harriet Maria [née Pemberton] (born 1794–died 1841), English home-maker
- Salusbury, Lady Sarah Burroughs [née King] (born 1721–died 1804), English home-maker
- Sancho, Elizabeth Bruce (born 1766–died 1837), English shopkeeper
- Sancho, William Leach Osborne (born 1775–died 1810), English bookseller, printer
- Sanderson, Reverend Robert, bishop of Lincoln (born 1587–died 1663), English churchman, theologian
- Sandys, Reverend Edwin (born 1643–died 1705), English churchman
- Sansom, John (flourished 1702–1717), English civil servant
- Sappho (pseudonym/initials used c. 1766), English home-maker
- The Satirist (founded 1807), English newspaper
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