Lives listing by occupation: politician
- Dupan, Jean Louis [senior] (born 1689–died 1756), Swiss politician
- Dupan, Jean Louis (born 1698–died 1775), Swiss politician
- Du Plaquet, père Charles Vincent, abbé Du Plaquet (born 1730–died 1811), French politician, churchman
- Duquesnoy, Adrien Cyprien (born 1759–died 1808), French lawyer, politician, translator
- Du Roveray, Jacques Antoine (born 1747–died 1814), Swiss politician
- Dusaulx, Jean Joseph (born 1728–died 1799), French scholar, classicist, academician, politician, revolutionary
- Du Terreaux, Charles Auguste (born 1725–died 1779), Swiss politician
- Duvall, Gabriel (born 1752–died 1844), American politician, lawyer, judge, civil servant
- Dwight, Thomas (born 1758–died 1819), American lawyer, politician
- Dyer, Eliphalet (born 1721–died 1807), American politician, lawyer
- Dyson, Jeremiah (born 1722–died 1776), English politician, member of Parliament
- Echeverría, José Tiburcio (died 1822), Colombian politician, diplomat
- Edgcumbe, Richard, 1st Baron Edgcumbe of Mount Edgcumbe (born 1680–died 1758), English politician, member of Parliament, civil servant
- Edwards, Bryan (born 1743–died 1800), English colonist, plantation-owner, politician, member of Parliament, academician
- Ellery, William (born 1727–died 1820), American merchant, politician
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