Lives listing by occupation: politician
- Coste, Jean François (born 1741–died 1819), French physician, army officer, politician
- Coutts, James (born 1733–died 1778), Scottish banker, politician, member of Parliament
- Cowper, William, 1st Earl Cowper (born c. 1665–died 1723), English politician, member of Parliament, aristocrat
- Cowper, Doctor William (born 1701–died 1767), English physician, antiquarian, academician, politician
- Coxe, Tench (born 1755–died 1824), American author, economist, journalist, politician
- Craggs, James [the elder] (born 1657–died 1721), English politician, member of Parliament, businessman, clothier
- Craggs, James [the younger] (born 1686–died 1721), English diplomat, politician, member of Parliament
- Cramer, Jean (born 1701–died 1773), Swiss lawyer, politician
- Cranch, Richard (born 1726–died 1811), American glassmaker, politician, tradesman
- Crassous, Jean Augustin (born 1755–died 1829), French lawyer, politician, revolutionary
- Craufurd, John, 18th laird of Auchinames (born 1742–died 1814), Scottish politician, member of Parliament, eccentric, gambler
- Craufurd of Auchenames, Patrick, 17th laird of Auchinames (born c. 1704–died 1778), Scottish politician, member of Parliament
- Creevey, Thomas (born 1768–died 1838), English politician, member of Parliament, diarist, author
- Croker, John Wilson (born 1780–died 1857), Irish politician, member of Parliament, essayist, author
- Crommelin, Jean Pierre (born 1716–died 1768), Swiss author, historian, politician, diplomat
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