Lives listing by occupation: politician
- Clive, Edward, 1st earl of Powis (born 1754–died 1839), English aristocrat, politician, member of Parliament, colonial governor
- Clotworthy, John, 1st Viscount Massereene (born c. 1595–died 1665), Irish politician, member of Parliament
- Clutterbuck, Thomas (born 1697–died 1742), English government minister, politician, member of Parliament
- Clymer, George (born 1739–died 1813), American merchant, politician
- Cobenzl, Johann Karl Philipp von, graf von Cobenzl (born 1741–died 1810), Austrian diplomat, politician, civil servant
- Coleman, Robert (born 1741–died 1825), Irish industrialist, manufacturer, politician
- Colepeper, John, 1st Baron Colepeper (born 1600–died 1660), English politician, member of Parliament
- Colleton, Sir Peter (born 1635–died 1694), English landowner, financier, politician, member of Parliament
- Collins, John (died 1795), Canadian politician, judge, civil servant, surveyor
- Colt, Peter (born 1744–died 1824), American businessman, politician
- Combe, Sir Harvey Christian (born 1752–died 1818), English businessman, politician, member of Parliament
- Compton, Spencer, earl of Wilmington (born c. 1674–died 1743), English politician, member of Parliament
- Compton, Spencer Joshua Alwyne, 2nd marquess of Northampton (born 1790–died 1851), English patron, academician, politician, member of Parliament
- Conduitt, John (born 1688–died 1737), English politician, member of Parliament
- Conolly, William (born 1662–died 1729), Irish politician, member of Parliament
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