Lives listing by nationality: Italian
- Royer, Joseph Nicolas Pancrace (born 1705–died 1755), Italian composer
- Ruzini, Zan Antonio (flourished 1744), Italian aristocrat, magistrate, civil servant
- Saint-Georges, Louis Ignace, comte de Foglizzo (flourished c. 1730), Italian politician
- Salieri, Antonio (born 1750–died 1825), Italian composer, conductor, musician, teacher
- Salvemini de Castiglione, Giovanni Francesco Mauro Melchior (born 1708–died 1791), Italian mathematician
- Salvioni, Luigi (flourished 1777–1788), Italian librettist
- Sambuca, Antonio (died 1767), Italian author, historian
- Sanità, Magistrato de Venezia alla (founded c. 1400), Italian government department, health official
- Santaniello, Ferdinando (flourished 1698–1708), Italian university teacher, physician
- Sarbeti, conte — di (flourished c. 1763), Italian [unknown occupation]
- Sarotti, Paolo (born 1633–died after 1689), Italian politician, diplomat, scientist, academician
- Sarpi, padre Paolo (born 1552–died 1623), Italian churchman, author, historian, scientist, lawyer, civil servant
- Savii alla Mercantia, Magistrato de Venezia (founded c. 1250), Italian government department, trade official
- Sbaraglia, Giovanni Girolamo (born 1641–died 1710), Italian university teacher, physician, anatomist
- Scarselli, Flaminio (born 1705–died 1776), Italian author, playwright, civil servant, university teacher, rhetorician, translator
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