Lives listing by nationality: English
- Clarke, James Stanier (born 1766–died 1834), English churchman, author, naval officer, librarian, academician
- Clarke, Mary [née Jepp] (born c. 1656–died c. 1705), English home-maker
- Clarke, Richard (flourished c. 1699), English [unknown occupation]
- Clarke, Samuel (born 1624–died 1669), English Orientalist, biblical scholar, theologian, author
- Clarke, Reverend Samuel (born 1626–died 1701), English churchman, Protestant, theologian, author
- Clarke, Samuel (flourished 1689–1704), English tailor, tradesman
- Clarke, Doctor William (born 1639–died 1684), English physician
- Clarke, William (flourished c. 1694), English [unknown occupation]
- Clavering-Cowper, George Nassau, 3rd Earl Cowper (born 1738–died 1789), English aristocrat, politician, member of Parliament, art critic, collector, arts-patron, science patron
- Clay, Joseph (born 1741–died 1804), English merchant, lawyer, politician
- Clayton, Charlotte, Lady Sundon [née Dyve] (born c. 1679–died 1742), English courtier
- Clayton, Thomas (flourished 1679–1687), English lawyer
- Clement, Thomas (flourished 1775–1800), English lawyer
- Clenche, Andrew (died 1692), English physician, academician
- Clendon, Reverend Thomas (died 1677), English churchman
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