Lives listing by nationality: English
- Chamberlaine, Richard (born c. 1707–died 1784), English naval officer, military surgeon, landowner
- Chamberlayne, William (born 1619–died 1689), English author, poet, physician
- Chamberlen, Hugh (born c. 1632–died after 1720), English physician, midwife, speculator, academician, author
- Chambers, Sir William (born 1723–died 1796), English architect, academician
- Champante, Sir John (born 1625–died c. 1712), English civil servant
- Champion, Richard (born 1743–died 1791), English porcelain manufacturer
- Chancery, Court of (founded c. 1450–disbanded 1873), English law court
- Chandler, Reverend Doctor Richard (born 1738–died 1810), English academic, historian, antiquarian
- Chapelle, Henry (flourished 1741–1764), English bookseller
- Chapman, Reverend Doctor Joseph (born c. 1743–died 1808), English academic, churchman, university administrator
- Chapone, Hester [née Mulso] (born 1727–died 1801), English journalist, educationalist, moralist
- Chapone, Sarah [née Kirkham] (born 1699–died 1764), English feminist, historian
- Chappell, Lucette (flourished 1789–1791), English home-maker
- Chappelow, Reverend Leonard (born 1744–died 1820), English academic, classicist, naturalist, author, poet
- Charles I, king of Great Britain and Ireland (born 1600–died 1649), English monarch
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