Lives listing with initial: S
- Sansom, John (flourished 1702–1717), English civil servant
- Sanson, Nicolas (born 1740–died 1789), French journalist, clerk
- Santaniello, Ferdinando (flourished 1698–1708), Italian university teacher, physician
- Santis de Lagrange, M. — (flourished c. 1769), French [unknown occupation]
- Sappho (pseudonym/initials used c. 1766), English home-maker
- Sarasin, Reverend Jean [senior] (born 1693–died 1760), Swiss churchman, Protestant
- Sarasin, Jean (born 1703–died 1778), Swiss churchman, Protestant
- Sarbeti, conte — di (flourished c. 1763), Italian [unknown occupation]
- sarde, un ministre (flourished 1753–1754), [unknown nationality & occupation]
- Sargeant, Nathaniel Peaslee (born 1731–died 1791), American judge, lawyer
- Sargent, Epes (born 1748–died 1822), American merchant, ship-owner, tax-official
- Sargent, Paul Dudley (born 1745–died 1828), American merchant, army officer
- Sargent, Winthrop (born 1753–died 1820), American soldier, civil servant, author
- Sarotti, Paolo (born 1633–died after 1689), Italian politician, diplomat, scientist, academician
- Sarpi, padre Paolo (born 1552–died 1623), Italian churchman, author, historian, scientist, lawyer, civil servant
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