Lives listing with initial: S
- Say, Jean Baptiste (born 1767–died 1832), French author, political economist, journalist, university teacher
- Say, Jean Honoré (born 1771–died 1799), French teacher
- Sayer, John (born c. 1750–died 1818), Canadian fur-trader, tradesman
- Sayward, Jonathan (born 1713–died 1797), American [unknown occupation]
- Sbaraglia, Giovanni Girolamo (born 1641–died 1710), Italian university teacher, physician, anatomist
- Scaliger, Joseph Juste (born 1540–died 1609), French author, scholar, classicist, Orientalist, academic, scholar, historian, religious controversialist
- Scapula, Johann (born 1540–died 1600), German philologist, scholar, classicist
- Scarburgh, Sir Charles (born 1615–died 1694), English physician, scientist
- Scarselli, Flaminio (born 1705–died 1776), Italian author, playwright, civil servant, university teacher, rhetorician, translator
- Schaack, Henry van (born 1733–died 1823), American [unknown occupation]
- Schaack, Peter van (born 1747–died 1832), American [unknown occupation]
- Schaak, Peter van (flourished 1767–1800), American politician
- Schaeffner, Adam Nepomuc (flourished 1761–1765), German student
- Schard, Johann (born 1660–died 1727), German alchemist, physician, courtier, mathematician, historian
- Schaub, Lady — (died 1793), French home-maker
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