Lives listing with initial: D
- Descamps, Jean Baptiste (born 1714–died 1791), French painter, educational founder, schoolteacher, historian, academician
- Descamps, Jean Baptiste Marc Antoine (born 1742–died 1836), French artist
- Descartes, René (born 1596–died 1650), French mathematician, philosopher
- De Scévole, M. — (flourished 1770–1780), [unknown nationality & occupation]
- Descévole, M. — (flourished 1772–1782), French literary critic, historian
- Deschamps, Euphrasie (flourished c. 1768), French home-maker
- Deschamps, Jean (born 1707–died 1767), German churchman, Protestant, journalist, translator
- Deschamps, Léger Marie (born 1716–died 1774), French freethinker
- Deschamps de Chaumont, père Joseph Nicolas, bishop of Genève-Annecy (died 1763), French churchman
- Descloseaux, Pierre Olivier (born 1732–died 1816), French notary
- Descréaux, M. — (flourished c. 1767), French [unknown occupation]
- Des Fontaines-Voutron, Daniel (flourished 1667–1674), French physician
- Desforges-Maillard, Paul (born 1699–died 1772), French lawyer, poet, academician
- Des Frays, Monsieur (flourished 1793–1803), French lawyer
- Desgouttes, Henri Zacharie (born 1762–died 1834), Swiss politician, revolutionary, author
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