Lives listing with initial: D
- Debeaune, Florimond (born 1601–died 1652), French mathematician, astronomer
- De Blaquiere, Eleanor [née Dobson] (born 1756–died 1831), English home-maker
- Deblois, Gilbert [senior] (died c. 1791), American [unknown occupation]
- Deborde, M. — (flourished c. 1778), French [unknown occupation]
- Debraw, John (died 1788), English apothecary, physician
- De Brucan, César Antoine, chevalier De Brucan (born 1741–died c. 1819), French aristocrat, émigré
- Debrus, Philippe (born 1696–died 1778), French banker
- De Bulkley, — (flourished 1753), [unknown nationality & occupation]
- Debure, Guillaume François (born 1732–died 1782), French publisher, bookseller, printer, bibliographer
- La Décade philosophique (founded 1794–disbanded 1807), French journal
- Decoste, M. — (flourished c. 1768), French business clerk
- Decrès, Denis, duc Decrès (born 1761–died 1820), French naval officer, government minister
- Decroix, Jacques Joseph Marie (born 1746–died 1826), French lawyer, civil servant, musicologist, collector, editor
- Defer de Maisonneuve, André (born 1749–died 1795), French publisher, bookseller
- Defoe, Daniel (born c. 1660–died 1731), English author, businessman, spy, soldier
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