Lives listing with initial: A
- Ast, William Frederick (flourished 1794–1799), German business agent
- Astell, James (flourished 1664–1701), English alchemist
- Astell, Mary (born 1666–died 1731), English feminist, author
- Asterism, the (active 1678), international secret society
- Astezati, Giovanni Andrea (born 1673–died 1747), Italian [unknown occupation]
- Astier, Hyacinthe Antoine d’, seigneur de Cromessière (born 1715–died 1786), French army officer
- Astle, Daniel (born c. 1743–died 1826), English churchman
- Astle, Thomas (born 1735–died 1803), English antiquarian, collector, archivist
- Aston, Francis (born 1645–died 1715), English academician
- Astruc, Jean François Antoine (born 1695–died 1780), French judge, lawyer
- Athenian Society (founded 1691), English journalistic club
- Atkins, — (flourished 1808–1829), English singer
- Atkins, Francis (flourished 1656–1657), English [unknown occupation]
- Atkinson, John (flourished 1735–1752), English publisher
- Atlee, William Augustus (born 1735–died 1793), American [unknown occupation]
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