Lives listing by occupation: physician
- Smith, Doctor John (born 1630–died 1679), English physician, medical author, author
- Smith, Doctor Ralph (flourished 1686–1689), English physician, merchant
- Smollett, Tobias (born 1721–died 1771), Scottish physician, surgeon, sailor, novelist, historian, travel-writer
- Smyth, James Carmichael (born 1742–died 1821), English physician
- Sömmerring, Doctor Samuel Thomas von (born 1755–died 1830), German physician, anatomist, anthropologist, palaeontologist, inventor
- Sorbière, Samuel (born 1615–died 1670), French physician, astronomer, tutor, academician, executor
- Spannut, Willem (born c. 1631), French physician
- Spon, Doctor Jacob (born 1647–died 1685), French Huguenot, physician, antiquarian, archaeologist, author, historian, travel-writer, historian
- Stahl, Georg Ernst (born 1660–died 1734), German physician, pharmacist
- Stark, William (born 1740–died 1770), English physician
- Staunton, Sir George Leonard, baronet (born 1737–died 1801), Irish physician, plantation-owner, diplomat, East India Company official, academician
- Stedman, Doctor John (died 1791), Scottish physician, author
- Steigerthal, Doctor Johann Georg (born 1666–died 1740), German physician, academician
- Stevenson, Alexander (born c. 1725–died 1791), Scottish physician
- Stevenson, John (born 1685–died 1757), Scottish physician
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