Lives listing by nationality: French
- Schoepflin, Josef Friedrich (flourished 1754–1762), French printer
- Scieux, Mme — de (flourished c. 1759), French home-maker
- Secondat, Charles Louis de, baron de Montesquieu (born 1689–died 1755), French magistrate, philosopher, academician
- Secousse, Daniel François (born 1691–died 1754), French author, historian, academician
- Sedaine, Michel Jean (born 1719–died 1797), French author, playwright, academician
- Sefond, — de [née Mesnard de Conichard] (flourished 1784), French home-maker
- Séguier, Anne Jacqueline Charlotte (born 1696), French home-maker
- Séguier, Jean François (born 1703–died 1784), French archaeologist, epigraphist, astronomer, botanist, academician
- Séguier, Sidoine Charles François, marquis de Saint-Brisson (born 1738–died 1773), French army officer, author
- Ségur, Louis Philippe de, comte de Ségur (born 1753–died 1830), French diplomat, politician, author, poet
- Seguy, M. — (flourished 1741–1743), French tutor
- Séguy, Joseph (born 1689–died 1761), French churchman, poet, academician
- Seignette, Pierre Henri (born 1735–died 1808), French pharmacist, academician
- Sélis, Nicolas Joseph (born 1737–died 1802), French university teacher, academician
- Sellier, Nicolas Henri (flourished 1720–1745), French notary
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