Lives listing by nationality: American
- Chase, Thomas (born 1739–died 1787), American [unknown occupation]
- Chauncy, Reverend Charles [the elder] (born 1592–died 1672), American churchman, university administrator
- Chauncy, Reverend Doctor Charles [the younger] (born 1705–died 1787), American churchman, author
- Cherokees, Commissioners to the (active 1761), American government department
- Chesley, Robert (flourished 1789), American civil servant, army officer
- Chester, John (born 1749–died 1809), American [unknown occupation]
- Chetwood, John (born 1736–died 1807), American lawyer, judge
- Chew, Benjamin (born 1722–died 1810), American [unknown occupation]
- Chew, Samuel (born 1660–died 1718), American landowner, merchant
- Childs, Francis (born 1763–died 1830), American newspaper editor
- Chilton, Charles (born 1741–died 1824), American politician, civil servant, surveyor
- Chiswell, John (flourished 1710–1766), American landowner, mine owner
- Choate, John (born 1737–died 1791), American [unknown occupation]
- Choate, Stephen (born 1727–died 1815), American farmer, politician
- Chrystie, James (born 1750–died 1807), American [unknown occupation]
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